四川大学LDSports乐动体育(中国)官方网站
师资力量

刘波     教授、博士生导师

研究方向:具有重要生物活性的复杂天然产物全合成;天然产物分子探针的生物学功能开发;合成导向的反应方法学研究

联系方式:028-85413712          Email:chembliu@scu.edu.cn

个人主页:点击进入

简历         

1994.9-1998.7  于西南师范大学化学化工学院学习,环境学专业;获理学学士学位

1998.9-2001.7  于中科院成都有机化学研究所学习,有机合成专业,主要从事不对称催化反应研究;获理学硕士学位;

导师:冯小明 研究员;蒋耀忠 研究员

2001.9-2004.7  于中科院上海有机化学研究所学习,有机合成专业,主要从事天然产物全合成研究;获理学博士学位;

导师:周维善 研究员

2004.9-2007.3  于美国德克萨斯大学西南医学中心作博士后研究,主要从事过渡金属催化的反应研究及天然产物全合成;

导师:Prof. Jef K. De Brabander

2007.6至今    于四川大学LDSports乐动体育(中国)官方网站从事教学和科研

主要研究方向   

1. 具药用潜力的复杂天然产物合成

2. 合成导向的反应方法学

3. 药物化学

科研项目

1. 天然产物全合成,国家杰出青年科学基金,2020-2024

2. 具微管稳定活性的taccalonolides天然产物的合成研究,国家自然科学基金面上项目(2019-2022)

3. 基于去芳香化/[5+2]环加成策略的二萜及其类天然产物合成研究,国家自然科学基金面上项目(2017-2020

4. 具有重要药用价值的多环天然产物的高效合成,国家自然科学基金重大项目(2013-2017)。 参与

5. 瑞香烷型二萜Trigoxyphin A的全合成研究,国家自然科学基金面上项目(2012-2015),项目负责人。

6. 具有重要生物活性的天然产物的化学合成,国家重点基础研究计划(科技部973计划, 2010-2014)。

7. 四川大学优秀青年学者科研基金(B类),2011-2014

8. 天然产物Chlorahololide A(钾离子通道抑制剂)的全合成研究,国家自然科学基金面上项目(2009-2011),项目负责人。

9. 教育部新世纪优秀人才支持计划(2009-2011项目负责人。

10. 抗真菌天然产物金粟兰内酯 A 的全合成研究,教育部留学回国人员基金(2009-2011),项目负责人。

11. 抗结核天然产物 Hirsutellones A-F 的全合成研究,国家自然科学基金青年基金项目(2008-2010),项目负责人。

获得奖励

1. 教育部自然科学一等奖(2010),第四完成人

2. 国家自然科学基金委优秀青年基金(2013

3. 中国化学会维善天然产物合成化学奖(2015

4. 国家自然科学基金委杰出青年基金获得者(2019

5. 中国化学会高级会员(2020

6. 国务院政府特殊津贴(2020

7. 第十二批四川省学术与技术带头人(2018年)

8. Thieme Chemistry Journal Award 2014

9. ACP Lectureship Awards to Japan & Malaysia (2014)

10. ACP Lectureship Awards to Taiwan (2015)

11. ACP Lectureship Awards to Singapore (2016)

12. ACP Lectureship Awards to Taiwan (2018)

13. Organic Chemistry Frontier Emerging Investigator2016

14. Sci. Chin. Chem.最佳审稿人奖(2016

15. 四川大学优秀教师(2013-2014年度)

16. 四川大学青年科技人才奖(2014

17. 四川大学唐立新青年科学之星奖(2015

18. 四川大学本科优秀毕业论文(设计)三等奖指导教师(2016

19. 四川大学大学生创新创业教育优秀指导教师(2017

20. 四川大学拔尖创新人才培养优秀指导教师(2017

21. 四川大学优秀科技人才奖(B类)(2019

22. 四川大学2019届本科优秀毕业论文(设计)二等奖指导教师(2019

23. 四川大学教学成果奖一等奖(2021),第二完成人

24. 四川大学2021年度本科课堂教学质量优秀奖 (2022)

主要工作业绩

91. Wei Cao, Zhen Wang, Yan Hao, Tianli Wang, Shaomin Fu* and Bo Liu* . Total Synthesis of Sculponin U, A C-20 Oxygenated ent-Kaurane Diterpenoid, through Photoinduced Radical Cascade Cyclization. Angew. Chem. Int. Ed., 2023, accepted. DOI10.1002/anie.202305516 

90. Zhengsong Huang, Ganxing Huang, Xiao Wang, Song Qin, Shaomin Fu, Bo Liu*. Asymmetric Total Synthesis of Natural Lindenane Sesquiterpenoid Oligomers via a Triene as a Potential Biosynthetic Intermediate. Angew. Chem. Int. Ed., 2022, 134(17), e202204303.

·Highlighted by 化学谷 

89. Wang, X.; Wang, Z.; Ma, X.; Huang, Z.; Sun, K.; Gao, X.; Fu, S.; Liu, B.* Asymmetric Total Synthesis of Shizukaol J, Trichloranoid C and Trishizukaol A. Angew. Chem. Int. Ed., 2022, 134(17), e202200258.

·Selected as Hot paper

·Highlighted by Synfacts, Chem-Station, WileyChem, X-MOL, CBG News 

88. Tianzi Yu, Ying Sun, Canhui Tu, Song Chen, Ting Chen, Shaomin Fu and Bo Liu*. Total Synthesis of Crotophorbolone. Chem. Sci.2020, 11(27), 7177.

· Highlighted by ChemistryViews, CBG News.

87. Bo Liu*, Shaomin Fu, Chengying Zhou. Recent Progress on Naturally Occurring [4+2] Type Terpenoid Dimers: Sources, Bioactivities and Total Syntheses. Nat. Prod. Rep.2020, 37, 1627 - 1660. (review)

86. Biao Du, Zhengsong Huang,Xiao Wang, Ting Chen, Ying Sun, Shaomin Fu and Bo Liu.* A Unified Strategy toward Total Syntheses of Lindenane Sesquiterpenoid [4+2] Dimers. Nature Commun2019, 10, 1892.

·Selected as Editors’ Highlights

·Highlighted by CBG News.

85. Heping Deng, Wei Cao, Rong Liu, Yanhui Zhang, and Bo Liu*, Asymmetric Total Synthesis of Hispidanin A, Angew. Chem. Int. Ed., 2017, 56, 5849-5852.   

·Selected as Hot paper    

·Highlighted by Advanced Science News  

84. Changchun Yuan, Biao Du, Heping Deng, Yi Man, Bo Liu*, Total Synthesis of Sarcandrolide J and Shizukaol D: Lindenane Sesquiterpenoid [4+2] Dimers, Angew. Chem. Int. Ed., 2017, 56, 637-640.   

·Highlighted by Synfacts (2017, 227)

·Selected as Synfact of the month ·Highlighted by X-MOL

·Highlighted by Chin. J. Org. Chem.(有机化学,2017, 37, 774

83. Liqiang Song, Guili Zhu, Yongjiang Liu, Bo Liu*, Song Qin, Total Synthesis of Atisane-type Diterpenoids: Application of Diels-Alder Cycloadditions of Podocarpane-type Unmaskedortho-Benzoquinones, J. Am. Chem. Soc2015, 137, 13706-13714.    

·Highlighted by Synfacts (2016, 6)    

·Highlighted by X-MOL

82. Changchun Yuan, Biao Du, Li Yang, Bo Liu* Bioinspired Total Synthesis of Bolivianine: A Diels-Alder/ Intramolecular Hetero-Diels-Alder Cascade Approach, J. Am. Chem. Soc.2013, 135, 9291-9294.    

·One of Most Read Articles inJ. Am. Chem. Soc.

·Highlighted by Synfacts (2013, 915)

·Selected as Synfact of the month

·Highlighted by Chin. J. Org. Chem.(有机化学,2013, 33, 2028

·Highlighted by RSC/Chemistry World (2013-06-27)  

81. Xuan Huang, Liqiang Song, Jiao Xu, Guili Zhu, Bo Liu* Asymmetric Total Synthesis of Leucosceptroid B, Angew. Chem. Int. Ed. 2013, 52, 952-955.  

·Highlighted by Synfacts (2013, 246)

·Highlighted by Chin. J. Org. Chem.(有机化学,2013, 33, 654

80. Yunzhou Li, Shaomin Fu* and Bo Liu.* Asymmetric Syntheses of ent-Pimarane Diterpenoids. Org. Biomol. Chem., 2023, ASAP.

79. Cichang Ling, Zhengsong Huang, Yuqiao Zhou, Shaomin Fu* , and Bo Liu*.  Alternative Construction of the Core of Lindenane Sesquiterpenoid. Chin. J. Chem., 2023, ASAP.

78. Lizhi Xun, Zhijiang Zhang, Yuqiao Zhou, Song Qin*, Shaomin Fu*, and Bo Liu. Stereo-divergent Construction of [5, 5]-Oxaspirolactone of Phainanoids. J. Org. Chem., 2023, 88, 3987-3991.

77. 夏梦伟,付绍敏*,刘波*。四环素类抗生素药物的发现、发展与合成:源于天然产物,用于人类健康。《中国科学:化学》, 2023, 53, 485-502.

76. Guoshen Shaomin Fu*., Bo Liu*. Oxime Ester-Enabled Anti-Markovnikov Hydrosilylation of Alkenes. Chem. Commun., 2022, 58(87), 12204-12207.

75. Rong Liu, Mengwei Xia, Cichang Ling, Shaomin Fu*, Bo Liu*. Construction of the Tetracyclic Core Structure of Dysiherbols A−C. Org. Lett., 2022, 24(8), 1642-1646. Highlighted by CBG 资讯.  

· Highlighted by CBG News

74. Shaomin Fu, Bo Liu*. Chiral Pool Guided Syntheses of Polycyclic Natural Products. Chin. J. Chem., 2022, 40(3), 407-418. 

72.  Ying Xie, Wei Huang, Song Qin, Shaomin Fu* and Bo Liu *, Catalytic Radical Cascade Cyclization of Alkene-Tethered Enones to Fused Bicyclic Cyclo- propanols. Org. Chem. Front., 2021, 8, 6678-6686.

72. Zhuang Wang, Wenhan Zhang, Bo Liu.* Computational Analysis of Synthetic Planning: Past and Future. Chin. J. Chem., 2021, 39, 3127-3143.

71. Chong Sun, Rong Liu, Mengwei Xia, Ying Hou, Xumei Wang, Jin-jian Lu, Bo Liu,* Xiuping Chen.* Nannocystin Ax, a natural elongation factor 1 α  inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells. Toxicol. Appl. Pharm., 2021, 420, 115535.

70.Ying Hou, Rong Liu, Mengwei Xia, Chong Sun, Bingling Zhong, Jie Yu, Nana Ai, Jin-Jian Lu, Wei Ge, Bo Liu*, Xiuping Chen*, Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase independent apoptosis through cyclin D1 downregulation in colon n vivo, Pharmacol. Res., 2021, 137, 105870.

69. Yi Man, Chengying Zhou, Shaomin Fu*, and Bo Liu*. Synthetic Study Aiming at the Tricyclic Core of 12- epi -JBIR-23/24. Org. Lett., 2021, 233151-3156.

68. Guanggen Liu, Zhijiang Zhang, Shaomin Fu*, Bo Liu*. Asymmetric Total Synthesis of Rumphellclovane E. Org. Lett., 2021, 23, 290. These authors contribute equally to this article. Top ten downloaded article in Organic Letters in December 2020. Highlighted by synfacts, Synfacts 2021, 17(03), 248.

67. Ying Sun, Menqin Hu, Shaomin Fu*, Bo Liu*. Recent Advances in Alkaline Earth Metal Enabled Syntheses of Heterocyclic Compounds. Org. Biomol. Chem., 2020, 18, 6443 - 6466. (review).

66. Wei Cao, Bo Liu*, Total Synthesis of Farnesin through Excited-State Nazarov Cyclization (Highlight), Chin. J. Org. Chem. 2020, 40, 2173-2175.

65. Guizhou Yue, Bo Liu*, Research Progress on [3+n](n >= 3) cycloaddition of 1,3-Diploes, Chin. J. Org. Chem. 2020, 40, 3132-3153.

64. Xin Liu, Yiying Zhang, Hongwei Gao, Ying Hou, Jin-jian Lu, Yulin Feng, Qiongming Xu, Bo Liu, Xiuping Chen*, Induction of an MLKL mediated non-canonical necroptosis through reactive oxygen species by tanshinol A in lung cancer cells, Biochem. Pharmacol. 2020, 171, 113684.

63. Shaomin Fu, Bo Liu. Recent Progress on Synthesis of Limonoids and Limonoid-like Natural Products. Org. Chem. Front., 2020, 7(14), 1930. (review).

62. Guili Zhu, Chengying Zhou, Song Chen, Shaomin Fu*, Bo Liu*. Construction of BCDEF Core of Andilesin C. Org. Lett., 2019, 19, 7809.

61. Song Chen, Ting Chen, Guanggen Liu, Xiao Wang, Guili Zhu, Yongjiang Liu, Shaomin Fu* and Bo Liu*. Total synthesis of (±)-epi-stemodan-13α,17-diol. Org. Biomol. Chem., 2019, 17, 4711.

60. Ting Chen, Song Chen, Shaomin Fu *, Song Qin, Bo Liu*. Carbon-oxygen homo-coupling of 2-naphthols through electrochemical oxidative dearomatization. Synlett., 2019, 30, 903.

59. Rong Liu, Mengwei Xia, Yanhui Zhang, Shaomin Fu*, Bo Liu*. The Journey of Total Synthesis Toward Nannocystin Ax. Tetrahedron, 2019, 75, 1781-1794. Zhou Weishan Issue.

58. Yongjiang Liu, Yanhui Zhang, Xiao Wang, Shaomin Fu*, Bo Liu*. Synthesis of polycyclic frameworks through Iron-catalyzed intramolecular [5+2] cycloaddition. Synlett, 2018, 29(15): 1978.

57. Yi Man, Shaomin Fu*, Juan Chen, and Bo Liu*. Total synthesis and structural revision of an isopanepoxydone analog isolated from Lentinus strigellus. Org. Biomol. Chem., 2018, 16, 5043-5049.

56. Jing Feng, Tianzi Yu, Zhijiang Zhang, Jinpeng Li, Shaomin Fu, Juan Chen, and Bo Liu *. Asymmetric synthesis of the fully functionalized six-membered ring of trigoxyphin A. Chem. Comm., 2018, 54, 7665-7668. Highlighted by X-MOL.

55. Jing Feng, Hongli Yin, Yi Man, Shaomin Fu* and Bo Liu*. Asymmetric Synthesis of the Ring A Substructure of Genkwadane A. Chin. J. Chem. 2018, 36, 831-836. Selected as back cover paper.

54. Man Yi, B Liu. Progress in Total Syntheses of Antimalignant Pleural Mesothelioma Compounds. J. Chin. Chem. Soc., 2018, 65(3), 301-311.

53. Yongjiang Liu, Xiao Wang, Song Chen, Shaomin Fu and Bo Liu*. Iron-Catalyzed Intramolecular Perezone-Type [5+2] Cyclo- addition: An Access to Tricyclo [6.3.1.01,6] dodecane. Org.Lett., 2018, 20(10), 2934-2938. 

52. Asymmetric Synthesis of Hispidanin A and the Related Diterpenoids.Wei Cao, Heping Deng, Ying Sun, Bo Liu, Song Qin. Chem. Eur. J., 2018, 24, 9120-9129.

51. Chen, Juan; Liu, Bo:Total Synthesis of Natural Terpenoids: Inspired but Not Limited by Biohypothesis. Synlett, 2018, 29(7), 863.

50. Ze Meng, Bo Liu*, Total synthesis of five natural eremophilane-type sesquiterpenoids, Org. Biomol. Chem., 2018, 16, 957-962.

49. Changchun Yuan*, Bo Liu*, Total Synthesis of Natural Products via Iridium Catalysis, Org. Chem. Front., 2018, 5, 106-131.

48.Yan-Hui Zhang, Rong Liu, Bo Liu*Total Synthesis of Nannocystin Ax, Chem. Commun., 2017, 53, 5549-5552.

47. Changchun Yuan, Biao Du, Miao-Miao Xun, Bo Liu*, Oxidative Cleavage of Hydroxamic Acid Promoted by Sodium Periodate, Tetrahedron, 2017, 73, 3622-3628.

46. Guili Zhu, Bo Liu*, Synthesis of derivatives of podocarpane-type diterpenoids through Diels-Alder cycloaddition and photo-decarbonylation from unmasked ortho-benzoquinone, Tetrahedron, 2017, 73, 4070-4075.

45. Guili Zhu, Sachin B. Wadavrao, Bo Liu*, Divergent total synthesis of atisane-type diterpenoids, Chem. Rec., 2017, 17, 584-596.

44. Zhijiang Zhang, Bo Liu*, Total synthesis and confirmation of the revised structures of jiangrines A, C and D, Org. Biomol. Chem., 2017, 15, 207-212.

43. Jinpeng Li, Changchun Yuan, Biao Du, Bo Liu*, an Alternative Total Synthesis of Bolivianine, Chin. Chem. Lett. 2017, 28, 113-116.

42. Zhijiang Zhang, Bo Liu*, Total Synthesis of Proposed Structures of Jiangrines C and D, Sci. Chin. Chem. 2016, 59, 1205-1210.

41. Hongli Yin, Zhe Meng, Bo Liu*, Construction of the Core Structure of Trichotomone, Synthesis, 2016, 48, 3951-3956.

40. Heping Deng, Wei Cao, Zhijiang Zhang, Bo Liu*, Asymmetric Synthesis and Absolute Stereochemistry of A Labdane-type Diterpenoid Isolated from the Rhizomes of Isodan yuennanensis, Org. Biomol. Chem. 2016, 14, 6225-6230.

39. Li Yang, Liqiang Song, Chong Huang, Mingzheng Huang, Bo Liu*, Exploiting Ortho- Substitution Effect on Formation of Oxygen-containing [10] Paracyclophane through Ring-Closing Metathesis, Org. Chem. Front. 2016, 3, 319-323.

38. Rong Liu, Jing Feng, Bo Liu*, Synthetic Progress of Daphnane-type Diterpenoids, Acta Chim. Sin. 2016, 74, 24-43.

37. Tianzi Yu, Bo Liu*, Asymmetric Total Synthesis of 3-Furanoeudesmene, A Metabolite from Antarctic Gorgonian and Determination of Its Absolute Configuration, Chin. J. Org. Chem. 2015, 35, 2157-2161.

36. Jiao Xu, Bo Liu* Total synthesis of norleucosceptroids F and G, Chin. Chem. Lett. 2015, 26, 1341–1344.

35. Guili Zhu, Rong Liu, Bo Liu*, Total Synthesis of Atisane-type Diterpenoids and Related Diterpenoid Alkaloids, Synthesis. 2015, 47, 2691-2708. (Invited review)

34. Li Yang, Jing Feng, Jinpeng Li, Bo Liu*, Total synthesis of heliespirone B, Tetrahedron Lett. 2015, 56, 4931-4933.

33. Liqiang Song, Chong Huang, Mingzheng Huang, Bo Liu*, Toward the synthesis of hirsutellone B via an intramolecular Diels-Alder /ketene-trapping strategy, Tetrahedron 2015, 71, 3603-3608.

32. Yang Yang, Jinpeng Li, Biao Du, Changchun Yuan, Bo Liu*, Song Qin*, An Entry to Vinylcyclopropane through Palladium-catalyzed Intramolecular Cyclopropanation of Alkenes with Unstabilized Allylic tosylhydrazones, Chem. Commun. 2015, 51, 6179-6182.

31. Jing Feng, Bo Liu*, Formal Carbo [3+3] Annulation and Its Application in Organic Synthesis, Tetrahedron Lett. 2015, 56, 1474-1485.

30. Li Yang, Guizhou Yue, Changchun Yuan, Biao Du, Heping Deng, Bo Liu*, Synthetic Studies toward Lindenane-Type Sesquiterpenoid Dimers, Synlett. 2014, 25, 2471-2474.

29. Hai Tong, Bo Liu*, A Diels-Alder Approach toward the scaffolds of Polycyclic sesquiterpenoids with 2-Pyrone, Synlett. 2014, 25, 681-686.

28. Biao Du, Changchun Yuan, Tianzi Yu, Li Yang, Yang Yang, Bo Liu*, Song Qin* Asymmetric Total Synthesis of Onoseriolide, Bolivianine and Isobolivianine, Chem. Eur. J. 2014, 20, 2613-2622.

27. Biao Du, Changchun Yuan, Langzhong Zhang, Li Yang, Bo Liu* Deprotection of 1,3-Oxathiolanes to Ketones Promoted by Base, Tetrahedron Lett. 2013, 54, 2217-2220.

26. Guizhou Yue, Xuan Huang, Bo Liu* Progress in the Total Synthesis of trans-Hydrindane- Containing Terpenoids, Chin. J. Org. Chem. 2013, 33, 1167-1185.

25. Jing Feng, Guili Zhu, Bo Liu*, Xiangdong Zhou* Expedient Synthesis of (R)-Curcuphenol: A Chiral Pool Strategy, Chin. J. Chem. 2013, 31, 23-26.

24. Guizhou Yue, Li Yang, Changchun Yuan, Biao Du, Bo Liu* Progress in Total Syntheses of Lindenane-type Sesquiterpenoids and Their Dimers, Chin. J. Org. Chem. 2013, 33, 90-100.

23. Hang Su, Ting Zhou, Bo Liu* Total Synthesis of (±)-Spirobenzofuran, Synlett. 2013, 615-618.

22. Changchun Yuan, Li Yang, Biao Du, Bo Liu* A Base-promoted deprotection of 1, 3-dioxolanes to ketones, Tetrahedron Lett. 2012, 53, 6972-6976.

21. Guizhou Yue, Li Yang, Changchun Yuan, Biao Du, Bo Liu* Total Syntheses of Lindenane- type Sesquiterpenoids: (±)-Chloranthalactones A, B, F, (±)-9-Hydroxy Heterogorgiolide and (±)-Shizukanolide E, Tetrahedron, 2012, 68, 9624-9637.

20. Ting Zhou, Guili Zhu, Xuan Huang, Bo Liu* Zeise’s dimmer-catalyzed regioselective hydration of homopropargyl tertiary ether, Tetrahedron Lett. 2012, 53, 4955-4958.

19. Guizhou Yue, Li Yang, Changchun Yuan, Xiaoling Jiang, Bo Liu* Total synthesis of chloranthalactone A, Org. Lett. 2011, 13, 5406-5408. (one of Most Read Articles of OL in September, 2011)

18. Yongjiang Liu, Chong Huang, Bo Liu* Asymmetric total syntheses of heliannuol E and epi-heliannuol E, Tetrahedron Lett. 2011, 52, 5802-5804.

17. Chong Huang, Wenhan Zhang, Bo Liu* Racemic and enantioselective total synthesis of heliespirones A & C, Sci. China. Chem. 2011, 54, 43-55.

16. Mingzheng Huang, Liqiang Song, Bo Liu* Construction of the Cyclophane Core of the Hirsutellones via a RCM Strategy, Org. Lett. 2010, 12, 2504-2507.

15. Chong Huang, Bo Liu* Asymmetric total synthesis ent-heliespirones A & C, Chem. Commun. 2010, 46, 5280-5282.

14. Daxing Yang, Jianfeng Huang, Bo Liu* Platinum-Catalyzed Regioselective Formation of β-Alkoxy Ketones from Internal Alkynes, Eur. J. Org. Chem. 2010, 4185-4188.

13. Jianfeng Huang, Xuan Huang, Bo Liu* Gold-catalyzed synthesis of nitrogen-containing heterocycles from ε-N-protected propargylic esters, Org. Biomol. Chem. 2010, 8, 2697-2699.

12. Yunxiu Chen, Jianfeng Huang, Bo Liu* Total syntheses of the proposed structures of cuevaene A, Tetrahedron Lett. 2010, 51, 4655-4657.

11. Mingzheng Huang, Chong Huang, Bo Liu* Studies toward the total synthesis of the hirsutellones, Tetrahedron Lett. 2009, 50, 2797-2800.

 

Postdoctoral, Graduate and Undergraduate:

10. Jef K. De Brabander*, Bo Liu, Mingxing Qian Au(I)- and Pt(II)-Catalyzed Cyclo- etherification of ω-Hydroxy Propargylic Esters, Org. Lett. 2008, 10, 2533.

9. Xin Jiang, Bo Liu, Sylvain Lebreton, Jef K. De Brabander* Total Synthesis and Structure Revision of the Marine Metabolite Palmerolide A, J. Am. Chem. Soc. 2007, 129, 6386. (One of the Most-Accessed Articles in 2007

8. Bo Liu, Jef K. De Brabander* Metal-Catalyzed Regioselective Oxy-Functionalization of Internal Alkynes: An Entry into Ketones, Acetals, and Spiroketals, Org. Lett. 2006, 8, 4907.

7. De-Run Li, Dong-Hui Zhang, Cai-Yun Sun, Ji-Wen Zhang, Li Yang, Jian Chen, Bo Liu, Ce Su, Wei-Shan Zhou*, Guo-Qiang Lin* Total Synthesis of Phorboxazole B, Chem. Eur. J. 2006, 12, 1185.

6. Bo Liu, Wei-Shan Zhou* Towards the total synthesis of natural peloruside A: stereoselective synthesis of the backbone of the core, Org. Lett. 2004, 6, 71.

5. Bo Liu, Wei-Shan Zhou*, Stereoselective synthesis of the C21-C27 fragment of the phorboxazoles, Tetrahedron Lett. 2003, 44, 4933.

4. Bo Liu, Wei-Shan Zhou* The first stereoselective synthesis of orostanal, a novel abeo-sterol inducing apoptosis in leukemia cells, Tetrahedron. 2003, 59, 3379.

3.Zhigang Jiao, Xiaoming Feng*, Bo Liu, Fuxue Chen, Guolin Zhang, Yaozhong Jiang, Enantioselective Strecker reactions between aldimines and trimethylsilyl cyanide promoted by chiral N,N’-dioxides, Eur. J. Org. Chem. 2003 , 3818.

2. Bo Liu, Wei-Shan Zhou* The first stereoselective synthesis of orostanal, a novel abeo-sterol inducing apoptosis in leukemia cells, Tetrahedron Lett. 2002, 43, 4187.

1. Bo Liu, Xiaoming Feng*, Fuxue Chen, Guolin Zhang, Xin Cui, Yaozhong Jiang, Enantio- selective Strecker reaction promoted by chiral N–oxides, Synlett. 2001, 1551.

Book Chapter:

Bo Liu, Changchun Yuan, Biao Du in Strategies and Tactics in Organic Synthesis, Vol. 13 (Eds.: Michael Harmata), Elsevier, 2017, p. 161-216 Chapter 7

Patent:

2. 刘波,黄正松,付绍敏. 乌药烷倍半萜中间体、由该中间体制备的乌药烷型倍半萜多聚体及制备方法. 申请号:202111281934.3

1. Jef K. De Brabander, Xin Jiang, Bo LiuPalmerolides: Methods of preparation and derivatives thereof, US patent, US2008249162-A1; WO2008124072-A1; TW200906387-A; US7838691-B2.

 

关闭